Introduction
Duphalac is a well-known laxative used to treat constipation and related conditions. The active ingredient in Duphalac is lactulose, a synthetic sugar that helps soften stools and encourage regular bowel movements. This article provides a comprehensive guide on Duphalac, including its uses, dosage recommendations, side effects, and essential precautions to ensure safe use.
What is Duphalac?
Duphalac is a brand name for lactulose, a type of osmotic laxative that draws water into the intestines, softening stool and promoting regular bowel movements. It is generally used for:
- Chronic constipation relief
- Management of hepatic encephalopathy (a liver-related brain disorder caused by excess ammonia levels)
- Regulation of bowel movements in post-surgery or bedridden patients
- Supporting gut health by promoting beneficial bacteria in the intestines

How Duphalac Works
Duphalac contains lactulose, a synthetic sugar that is not absorbed by the body. When ingested, it travels to the colon, where gut bacteria break it down into acids. These acids help draw water into the intestines, making stools softer and easier to pass. Additionally, in patients with hepatic encephalopathy, lactulose lowers ammonia levels, preventing toxic buildup in the brain that can lead to confusion, tremors, or coma.
Dosage and How to Use Duphalac
The correct dosage of Duphalac varies depending on the condition being treated:
For Constipation
- Adults: 15-30 ml per day, which may be adjusted based on response.
- Children (1-6 years): 5-10 ml per day.
- Infants (below 1 year): 2.5-5 ml per day.
- Duphalac should be taken at the same time daily, preferably in the morning.
- It can be consumed with or without food, but drinking plenty of water enhances its effects.
- If constipation persists for more than three days, consult a doctor.
For Hepatic Encephalopathy
- Starting dose: 30-45 ml, taken three times daily.
- The dosage is adjusted to maintain 2-3 soft stools per day.
- It is sometimes used in combination with antibiotics like rifaximin to improve results.
Essential Usage Tips
- Shake the bottle well before each use.
- Use a measuring spoon or cup for accurate dosing.
- Duphalac works gradually, taking 24-48 hours to show effects.
- Overuse may result in diarrhea and dehydration.
Side Effects of Duphalac
While Duphalac is generally safe, some individuals may experience mild to moderate side effects, such as:
- Bloating and gas (common in the initial days of use)
- Diarrhea (if the dosage is too high)
- Abdominal cramps and discomfort
- Nausea or vomiting
- Electrolyte imbalances (rare but can occur with prolonged use)
Severe side effects such as persistent diarrhea, dehydration, or irregular heart rhythms require immediate medical attention.

Precautions and Safety Warnings
Before taking Duphalac, consider the following precautions:
- Diabetic patients should use it cautiously, as lactulose contains sugar derivatives.
- Duphalac is not recommended for individuals with galactosemia (a rare metabolic disorder).
- Pregnant and breastfeeding women should consult a doctor before use.
- Drink plenty of fluids while taking Duphalac to prevent dehydration.
- Individuals with intestinal blockages or severe abdominal pain should seek medical advice before use.
- Long-term users should monitor potassium and sodium levels to avoid electrolyte imbalances.
Duphalac vs. Other Laxatives
Duphalac is often compared to other common laxatives such as psyllium husk (Metamucil), bisacodyl (Dulcolax), and polyethylene glycol (MiraLAX). Each type has its own advantages and uses:
Comparison of Different Laxatives:
- Duphalac (Lactulose): A gentle, slow-acting laxative suitable for long-term use and liver disease management.
- Psyllium Husk (Metamucil): A natural fiber supplement that bulks up stools.
- Bisacodyl (Dulcolax): A stimulant laxative that triggers bowel contractions, providing faster relief.
- Polyethylene Glycol (MiraLAX): Works similarly to Duphalac but lacks ammonia-reducing effects for liver patients.
Duphalac is preferred for chronic constipation and liver-related issues because it is non-habit-forming and improves gut health over time.
Is Duphalac Safe for Long-Term Use?
- Duphalac can be safely used for an extended period under medical supervision.
- It does not lead to dependency, unlike stimulant laxatives.
- Long-term users should have regular medical check-ups to monitor digestive health.
- It supports a balanced gut microbiome, benefiting overall digestion.

Frequently Asked Questions (FAQs)
1. Can I take Duphalac daily?
Yes, Duphalac can be taken daily for chronic constipation, but the dose should be adjusted based on bowel movement response.
2. How soon does Duphalac start working?
Duphalac typically takes 24-48 hours to relieve constipation, though some people may notice effects sooner.
3. Is Duphalac safe for pregnant women?
Yes, but pregnant women should use Duphalac only under medical supervision to ensure safety.
4. Can I mix Duphalac with juice?
Yes, Duphalac can be mixed with water, juice, or milk to improve taste, especially for children.
5. What happens if I miss a dose of Duphalac?
Take the missed dose as soon as you remember, but do not double up if it is almost time for your next scheduled dose.
6. Is Duphalac suitable for children?
Yes, Duphalac is safe for children, but the correct dosage should be determined by a doctor based on age and medical condition.
7. Can I stop taking Duphalac once my constipation is relieved?
Yes, but it is recommended to adjust the dosage gradually instead of stopping suddenly, especially for chronic constipation.
8. What should I do if I experience severe diarrhea?
Reduce your dosage and consult a doctor if diarrhea persists to prevent dehydration.
Conclusion
Duphalac is an effective and safe laxative for treating constipation and managing hepatic encephalopathy. Its ability to draw water into the intestines ensures soft, regular bowel movements while also supporting gut health. Unlike stimulant laxatives, Duphalac does not cause dependency, making it ideal for long-term use. However, it is important to take the correct dosage and maintain adequate hydration for the best results.
If you experience persistent constipation or digestive issues, consult a healthcare provider before starting or adjusting your Duphalac dosage.
For more expert health advice and medical insights, visit Healoopedia.com.
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